Search results for "Phosphorus atom"
showing 9 items of 9 documents
Reappraising Schmidpeter's bis(iminophosphoranyl)phosphides: coordination to transition metals and bonding analysis
2020
The synthesis and characterization of a range of bis(iminophosphoranyl)phosphide (BIPP) group 4 and coinage metals complexes is reported. BIPP ligands bind group 4 metals in a pseudo fac-fashion, and the central phosphorus atom enables the formation of d0–d10 heterobimetallic complexes. Various DFT computational tools (including AIM, ELF and NCI) show that the phosphorus–metal interaction is either electrostatic (Ti) or dative (Au, Cu). A bridged homobimetallic Cu–Cu complex was also prepared and its spectroscopic properties were investigated. The theoretical analysis of the P–P bond in BIPP complexes reveals that (i) BIPP are closely related to ambiphilic triphosphenium (TP) cations; (ii) …
Novel heterobimetallic radiotheranostic: preparation, activity, and biodistribution.
2014
A novel Ru(II) (arene) theranostic complex is presented. It is based on a 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid macrocycle bearing a triarylphosphine and can be tracked in vivo by using the γ emission of (153) Sm atoms. Notably, the heteroditopic ligand can be selectively metalated with ruthenium at the phosphorus atom despite the presence of other functionalities that are prone to metal coordination. Subsequent labeling with radionuclides such as (153) Sm can then be performed easily. The resulting heterobimetallic complex exhibits favorable solubility and stability properties in biologically relevant media. It also shows in vitro cytotoxicity in line with that expected …
ChemInform Abstract: Designing P*-Chirogenic Organophosphorus Compounds: From Ligands to Organocatalysts
2015
The interest of organophosphorus compounds bearing chirality on the phosphorus atom has greatly expanded in last decade, due to the development of efficient stereoselective synthetic methods, using...
Designing P*-chirogenic Organophosphorus Compounds: from Ligands to Organocatalysts
2015
The interest of organophosphorus compounds bearing chirality on the phosphorus atom has greatly expanded in last decade, due to the development of efficient stereoselective synthetic methods, using...
The [1,2,3]triazolo[1,5-a]pyridine ring: a sensitive sensor for the electronic profile of phosphorus substituents.
2009
The unique nature of the [1,2,3]triazolo[1,5-a]pyridine reveals without any external perturbation the electronic contribution of various substituents to the phosphorus atom in phosphines, based on the equilibrium of two possible ring-chain isomers.
Stereospezifische Überführung chiraler acyclischer tertiärer Phosphinsulfide in die entsprechenden tertiären Phosphinoxide mit Dimethylsulfoxid (DMSO)
1975
Die Uberfuhrung chiraler acyclischer tertiarer Phosphinsulfide in die entsprechenden tertiaren Phosphinoxide mit DMSO in saurer Losung erfolgt unter vollstandiger Inversion der Konfiguration am zentralen Phosphoratom. Aufgrund dieses stereochemischen Verlaufs wird ein Mechanismus fur die Reaktion zur Diskussion gestellt. Stereospecific Conversion of Chiral Acyclic Tertiary Phosphine Sulfides into the Corresponding Tertiary Phosphine Oxides by Means of Dimethyl Sulfoxide (DMSO) The conversion of chiral acyclic tertiary phosphine sulfides into the corresponding tertiary phosphine oxides by means of DMSO in acidic solution proceeds with complete inversion of configuration at the central phosph…
Bis(pentamethylcyclopentadienyl)-Substituted Phosphanes: Synthesis and Structure
1998
The bis(1,2,3,4,5-pentamethyl-1,3-cyclopentadien-1-yl)phosphanes 3−7 are formed in good yields by the reaction of the halogenophosphanes 2a or 2b with the appropriate nucleophile. Following another route, the dialkylaminobis(pentamethylcyclopentadienyl)phosphanes 11a−c have been synthesized by the treatment of dichloro(dialkylamino)phosphanes with two equivalents of (pentamethylcyclopentadienyl)lithium. The compounds 3−11 have been characterized by multinuclear NMR spectroscopy and 3, 5, 6, and 11a have also been characterized by single-crystal X-ray diffraction studies. The molecular structure of 11a is governed by steric congestion, which typically would lead to a parallel arrangement of …
3.17 Synthetically Derived Auxiliaries: Phosphorus Derivatives
2012
This chapter aims to give an overall view of chiral-pool based asymmetric synthesis of organophosphorus compounds more particularly bearing the chirality on the phosphorus atom (P-stereogenic). The enantiomerically pure organophosphorus compounds can be obtained either by resolution of the racemate or by stereoselective synthesis using particularly ephedrine or sparteine as the main chiral auxiliaries and borane as a P(III)-protecting group.
ChemInform Abstract: nBuLi-Mediated Hydrophosphination: A Simple Route to Valuable Organophosphorus Compounds.
2010
A straightforward synthesis of homoallyl- and allylphosphanes has been developed using nBuLi-mediated hydrophosphination of conjugated dienes. In all the cases the phosphorus atom of the reacting phosphane attacked the sterically less demanding side of the diene exclusively. In addition, high regioselectivities towards 1,2- or 1,4-addition products were observed depending on the nature of the dienes. This hydrophosphination reaction was extended to a variety of substrates such as styrene derivatives, alkynes and 1,3,5-cycloheptatriene. The structures of three hydrophosphination products were confirmed by X-ray diffraction studies.